Table 1

Baseline and Procedural Variables According to the Occurrence of NOP-LBBB (n = 668)

No NOP-LBBB
(n = 589)
NOP-LBBB
(n = 79)
p Value
Clinical characteristics
 Age, yrs81 ± 878 ± 90.006
 Male286 (48.6)39 (49.4)0.905
 Body mass index, kg/m226 ± 627 ± 60.200
 Hypertension473 (80.3)71 (89.9)0.040
 Diabetes mellitus169 (28.7)35 (44.3)0.005
 COPD161 (27.3)22 (27.8)0.923
 NYHA functional class >II452 (76.7)62 (78.5)0.730
 eGFR <60 ml/min260 (44.1)33 (41.8)0.719
 Coronary artery disease401 (68.1)58 (73.4)0.261
 Previous CABG189 (32.1)32 (40.5)0.135
 STS-PROM score, %7.9 ± 4.97.6 ± 4.60.568
 Log EuroSCORE, %21.2 ± 14.120.8 ± 13.90.844
Echocardiography
 LVEF, %56 ± 1356 ± 110.841
 Mean gradient, mm Hg47 ± 1745 ± 170.380
 Aortic valve area, cm20.60 (0.50–0.77)0.62 (0.55–0.78)0.504
 PSAP >60 mm Hg75 (12.7)12 (15.2)0.508
Procedural variables
 Procedural success531 (90.2)70 (88.6)0.668
 Valve in valve25 (4.2)3 (3.8)0.999
 Approach
  Transfemoral333 (56.5)30 (38.0)0.001
  Transapical237 (40.2)49 (62.0)
  Transaortic19 (3.2)0
 Prosthesis type
  Cribier-Edwards37 (6.3)2 (2.5)0.440
  Edwards Sapien299 (50.8)46 (58.2)
  Sapien XT247 (41.9)31 (39.2)
  Sapien 36 (1.0)0
 Prosthesis size, mm
  20–23274 (46.5)35 (44.3)0.041
  26294 (49.9)36 (45.6)
  2921 (3.6)8 (10.1)
In-hospital outcomes
 Moderate or more residual AR74 (12.5)9 (11.4)0.763
 Myocardial infarction9 (1.5)1 (1.3)0.999
 Major vascular complications50 (8.4)7 (8.9)0.922
 Major or life-threatening bleeding124 (21.1)13 (16.5)0.342
 Dialysis5 (0.8)1 (1.3)0.532
 Stroke14 (2.4)4 (5.1)0.254
 Death29 (4.9)5 (6.3)0.594

Values are mean ± SD, n (%), or median (interquartile range).

AR = aortic regurgitation; CABG = coronary artery bypass graft; COPD = chronic obstructive pulmonary disease; eGFR = estimated glomerular filtration rate; Log EuroSCORE: Logistic EuroSCORE (European System for Cardiac Operative Risk Evaluation)-predicted risk of mortality; LVEF = left ventricular ejection fraction; NOP-LBBB = new-onset persistent left bundle branch block; NYHA = New York Heart Association; PASP = pulmonary artery systolic pressure; STS-PROM = Society of Thoracic Surgeons predicted risk of mortality.